What is Prader Willi Syndrome? Prader-Willi syndrome (PWS) is a genetic disorder that occurs in approximately one out of every 15,000 births. PWS affects males and females with equal frequency and affects all races and ethnicities. PWS is recognized as the most common genetic cause of life-threatening childhood obesity. PWS was first described by Swiss doctors Andrea Prader, Alexis Labhart, and Heinrich Willi in 1956 based on the clinical characteristics of nine children they examined. Causes of Prader Willi Syndrome: PWS is the result of an abnormality on chromosome 15. There are three ways that this can happen: • First, if there is a deletion of critical genes on a portion of the 15th chromosome. This happen in most cases. • Second, the entire chromosome from father is missing and there are instead, two chromosomes from the mother. This condition is known as uniparental disomy. • Third, there is an imprinting mutation on chromosome 15 contributed by the father...
Hello everyone, My name is Musharrafa Asad. I am a student pursuing M.Sc in Food Science and Nutrition. I started blogging to spread the correct knowledge and awareness about nutrition so that everyone is updated in this field.